Anastrozole first developed to treat breast cancer in postmenopausal women.
Anastrozole is a Non-steroidal aromatase inhibitor
Anastrozole irreversibly binds to the aromatase and blocking the conversion of testosterone to estrogen the synthesis of estrogen is essentially prohibited.
The drugs ability to block estrogen makes it a useful drug for breast cancer in women and the post-surgical breast cancer.
Anastrozole off label applications for men
There has been some study for anastrozole use by infertile men by balancing testosterone levels, maintaining a healthy sperm count and as a treatment in certain prostate cancers.
Off label use by doctors and pharmacists to assist healthy men on testosterone replacement therapy manage excessive estrogen with anastrozole for men.
Testosterone therapy has become more commonplace in order to give men a higher quality of life and prevent premature aging to preserve sexual function.
Some male athletes and bodybuilders who take anabolic steroids to build muscle are at increased risk of losing sexual function and or producing breast milk.
Anastrozole drug interactions allow steroid users to balance excessive estrogen production as a side effect of androgenic anabolic steroids.
An increase in estrogen levels may cause these unwanted female characteristics to develop
- A high-pitched voice
- Shrinking of the testicles or penis
- Breast enlargement (Gynecomastia)
While the root of these theories indicates studies on female animal test subjects, scientific research has derived a few conceptual benefits regarding anastrozole for men.
Aromatase inhibitors similar to anastrozole
Anastrozole, also known as Arimidex is an aromatase-inhibiting peptide with a molecular formula of C17H19N5. It has a molecular mass of 293.366.
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