Cardarine GW-501516 1000mg 99% purity

Score: 5.00 (votes: 3)
Reviews: 3
3

Cardarine Dosage scoop white scoop 45mg

Yellow dosing scoop 4mg-12mg.

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  • Weight
    5 g
  • SKU
    HD1A5L9Y02
  • UPC/ISBN
    7427009305791

Cardarine a SARM like no other

Cardarine is a proliferator activator receptor delta performance-enhancing drug.

It is proven to increase exercise endurance, accelerate fat loss without uncomfortable side effects. 

Enhanced glucose uptake raised insulin sensitivity results in hypertrophy of muscle.  

Peroxisome proliferator-activated receptor show promise with drastic improvements in cholesterol levels and triglycerides.

GW-501516 has significant heart health benefits and leads to improvements in blood pressure.

 

Cardarine has fantastic benefits, and through decades of underground use still does not have any side effects attributed to it.

The glucose uptake and resulting insulin sensitivity allow fat to be burned as fuel, thereby allowing weight loss.

 

Cardarine Results

Cardarines unique ability to improve overall health and well being was unmatched until GW0742 came along.

A 2015 study revealed that it uses body fat as energy in a very similar way when the body is in starvation mode.

In the same study, there was an increase in oxygen usage in slow twitch muscle fibres; in turn, overall endurance is enhanced.

GW501516 exercise mimetics

 

Cardarine Benefits 

  • Promotes a healthy liver function
  • Reducing recovery times from exercise
  • Inhibits cancer cell growth on the colon and breast tissue
  • No published side effects on healthy individuals
  • Reversal of type 2 diabetes while reducing obesity and high cholesterol levels.

 

Clinical studies even reversed metabolic abnormalities in obese men with the pre-diabetic state by up-regulating fatty acid oxidation.

Proposals for use in obesity and other related conditions with AICAR had good results in animal studies.

Cardarine Dosage

Mice were fed a steady diet of 5 mg/kg over periods lasting four weeks or 3-30 mg/kg/day for five months.

Not only did it increased running performance in mice regardless of training, but the magnitude of improvement was unexpectedly greater for untrained mice.

This finding could be due to different Cardarine dosage protocols, exhaustive running tests, or strain differences.  

More recently, a metabolomic study comparing three weeks of exercise alone and in combination with GW501516 confirmed the synergistic effect of the compound, with an endurance increase of 70%.

Moreover, in stable conditions, the mixture elicited an endurance increase of nearly 50%.

These new data highlight the possibility that exercise and GW501516 exert beneficial effects through two different mechanisms.

PPAR delta drugs regulate fat burning through some widespread mechanisms; it increases glucose uptake in skeletal muscle tissue and increases muscle gene expression, especially genes involved in preferential lipid utilization.

This shift changes the body’s metabolism to favour burning fat for energy instead of carbohydrates or muscle protein.

Potentially this allows a clinical application for obese patients to lose fat effectively without experiencing muscle loss.

Cardarine SARM also increases muscle mass, improved glucose tolerance and reduced fat mass accumulation were observed even in mice fed a very high-fat diet. Thus, GW501516 may have a protective effect against obesity.

Cardarine Review

In rats, binding of GW501516to PPARδ recruits the co-activator PGC-1a. The PPARδ/coactivator complex, in turn, up-regulates the expression of proteins involved in energy expenditure.

Furthermore, in rats treated with GW-501516, increased fatty acid metabolism in skeletal muscle and protection against diet-induced obesity and typed II diabetes was discovered.

In obese rhesus monkeys, GW501516 increased high-density lipoprotein (HDL) and lowered very-low-density lipoprotein (VLDL).

The mechanism by which PPARδ agonists increase HDL appears to be a result of increased expression of the cholesterol transporter ABCA1. 

Endurobol, also known as GW-501516 and GSK-516, is a PPARδ receptor agonist. Endurobol entered into clinical development as a drug candidate for metabolic diseases and cardiovascular diseases.

Name: Endurobol 

CAS#: 317318-70-0 

Chemical Formula: C21H18F3NO3S2 

Exact Mass: 453.068 

Molecular Weight: 453.4942 

Elemental Analysis: C, 55.62; H, 4.00; F, 12.57; N, 3.09; O, 10.58; S, 14.14

All products listed and provided through our website are intended for research purposes only. We do not promote the personal use of these products. Products and services provided by 99SARMS.com are not intended for use in food products or as any drug. Our products are not intended to treat, prevent, mitigate or cure any disease or medical condition.

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  • Wayne
    Mar 13, 2019, 22:33
    Fast to notice this on especially on the cardio it's like your the Energizer bunny, all while burning fat faster than expected.
  • Alex wim
    Feb 27, 2019, 16:10
    Really great product, after taking it for 4 days ive observed results.
  • Adam Moyer
    Feb 25, 2019, 11:54
    I found this product to be an incredible endurance booster, great for taking your cardio to the next level. Quality product from a quality company

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  • Brand
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