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CE-123 125mg (3,750 mg)

Score: 4.08 (votes: 12)

CE-123 ((S)-5-((benzhydrylsylfinyl)methyl)thiazole) is novel atypical dopamine reuptake inhibitor nootropic that enhances cognitive flexibility without producing impulsive behaviour unlike R-Modafinil.

  • $59.99
In stock

Modafinil vs CE-123

Modafinil is famous for its cognition, improving effects and has been extensively evaluated in healthy individuals and psychiatric disorders. Animals studies report effects on attention, executive functions, learning and memory.

The Working memory-enhancing effect of Modafinil has been demonstrated by employing distinct spatial memory tasks.
Effects of Modafinil on longterm memory after chronic or subacute administration has been reported as well.

CE-123 nootropic shows a unique enhancing effect on memory acquisition on day one after a single administration prior to training.
A second dose on day two prior to training shows an enhancing effect only at 1 mg/kg.

CE-123 is like Modafinil, and many other psychostimulants positively have a dose-dependent effect on cognition, learning and memory consolidation.

The structural modification of Modafinil in the design of CE-123 is on position five via a methylene bridge, resulting in increased metabolic stability of the compound.

CE-123 Nootropic has incredible pharmacokinetics with rapid uptake.
Moreover, CE-123 was detected in the brain at one-hour post-administration in levels almost twenty times higher than R-modafinil.

The data, along with a memory-enhancing effect observed, indicate that CE-123 presumably permeates across the blood-brain barrier and approaches its sites of action in vivo.

What is CE-123 Nootropic Powder

Reduced cognitive abilities are often characterized by an impairment of flexibility, i.e., the ability to switch from learned rules or categories that were important in certain contexts to different new modalities that rule the task.

R-modafinil and other drugs that target the dopamine transporter (DAT) are commonly used to enhance cognitive function. However, the availablity of drugs with limited specificity for DAT is a concern as this also blocks noradrenaline and serotonine transporters.

The new research chemical CE-123 is more DAT specific improves cognitive flexibility improving visuospatial attention and reducing impulsivity.

While R-Modafinil dosage of 10 mg/kg shows an increase in impulsivity, this was not seen with CE-123 at the same dosage.

Thus, CE-123 increases cognitive flexibility with diminished impulsivity compared to similar dopamine reuptake inhibtors.

This modafinil analog shows a unique enhancing effect on memory acquisition on day one after a single administration with dose-dependent effect on cognition, learning and memory consolidation.

This product is for research use only

Customer reviews
Average rating:

Score: 4.08 (votes: 12)
Rating of votes (12)
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  • Saturday, September 25, 2021, 16:00
    I didn't feel anything. I don't think it works.
    Friday, October 1, 2021, 15:14
    CE-123 enhances memory acquisition and memory retrieval, represented by significantly increased reference memory indices and shortened latency.

    Perhaps the testing parameters were off, it's not flmodafinil but is grteat stacked to it, more of an academic DAT than anything else
  • Sunday, October 18, 2020, 19:04
    Super fast delivery. Great customer service. The packaging is professional and sealed bottles.
  • Monday, January 13, 2020, 00:17
    I have been waiting for this top be back in stock YEAHHHH!
    • Weight
      25 g
    • SKU
    • UPC/ISBN
    • Mnf#/Vendor#
  • Brand
  • Nootropic
    30 x 125mg

Product questions

  • JDD
    Thursday, June 18, 2020, 07:01

    What would be the dosage for a research primate that weighs 180lbs?