Clomiphene citrate PCT

Interestingly some in the medical field believe it to be a viable alternative to raise testosterone levels in place of TRT altogether.

Clomiphene citrate 50 mg three times weekly may be diagnostic as well as therapeutic.

If the patient does not respond with at least a 75% increase in testosterone and a 100% increase in Luteinizing hormone.

Should it fail to raise hormone levels, further evaluation of the hypothalamic-pituitary area is warranted.

How does Clomiphene Work?

To understand how clomiphene works, you need to know how the pituitary controls the making of testosterone in the testis.

The pituitary releases a hormone called luteinizing hormone (“LH”) that stimulates the Leydig cells to produce testosterone.

Testosterone is made by Leydig cells in the testis.

Testosterone is converted to the female hormone estrogen.

Then estrogen tells the pituitary to stop making more Leutenizing Hormone.

This kind of negative feedback system is typical when it comes to how hormones work. 

By blocking estrogen at the pituitary the pituitary gland will make more Luteinizing Hormone (LH).

What that means is that now the Leydig cells in the testis will make more testosterone. 

In the case of injectable testosterone, the pituitary gets the signal that there is too much and luteinizing hormone takes a dive.

Clomid is proven to increase testosterone levels while preserving testis size and function. 

More recently younger men have been prescribed due to concerns about fertility.

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Information provided here for academic use only.